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Feeling irritable

MedGen UID:
5898
•Concept ID:
C0022107
•
Finding
Synonyms: Irritable Mood; Irritable Moods; Mood, Irritable; Moods, Irritable
SNOMED CT: Feeling irritable (55929007); Irritability (55929007); Fussiness (55929007)

Definition

Excited response to stimuli. [from NCI]

Professional guidelines

PubMed

Individual and common patterns in the order of symptom improvement during outpatient treatment for major depression.
Snippe E, Doornbos B, Schoevers RA, Wardenaar KJ, Wichers M
J Affect Disord 2021 Jul 1;290:81-88. Epub 2021 May 2 doi: 10.1016/j.jad.2021.04.097. PMID: 33993084
Identifying factors of psychological distress on the experience of pain and symptom management among cancer patients.
Baker TA, Krok-Schoen JL, McMillan SC
BMC Psychol 2016 Nov 2;4(1):52. doi: 10.1186/s40359-016-0160-1. PMID: 27806721Free PMC Article
Symptoms and impact of symptoms on function and health in patients with chronic obstructive pulmonary disease and chronic heart failure in primary health care.
Theander K, Hasselgren M, Luhr K, Eckerblad J, Unosson M, Karlsson I
Int J Chron Obstruct Pulmon Dis 2014;9:785-94. Epub 2014 Jul 18 doi: 10.2147/COPD.S62563. PMID: 25071370Free PMC Article

Recent clinical studies

Etiology

Exploring core symptoms and interrelationships among symptoms in children with acute leukemia during chemotherapy: A network analysis.
Fang J, Xu LL, Liu CQ, Zhu Z, Wang MX, Liu X, Liu Q, Huang HY, Lin Y
Support Care Cancer 2023 Sep 16;31(10):578. doi: 10.1007/s00520-023-08024-7. PMID: 37715817
Symptom prevalence, burden and correlates among people living with HIV in Vietnam: a two-centre self-report study.
Le Dai D, Pham TVA, Bui TTH, Than TNH, Pham VT, Luong NK, Harding R, Krakauer EL
AIDS Care 2022 Jul;34(7):887-893. Epub 2021 Jun 16 doi: 10.1080/09540121.2021.1922577. PMID: 34133248
Changes in the Network Structure of Post-traumatic Stress Disorder Symptoms Among Earthquake Exposed Adolescents in China: A 2-Year Longitudinal Study.
An Y, Hu CP, Zhao J, Chen Y, Wu X
Child Psychiatry Hum Dev 2021 Feb;52(1):104-113. doi: 10.1007/s10578-020-00995-6. PMID: 32342236
Quality of life and chemotherapy-related symptoms of Turkish cancer children undergoing chemotherapy.
Arslan FT, Basbakkal Z, Kantar M
Asian Pac J Cancer Prev 2013;14(3):1761-8. doi: 10.7314/apjcp.2013.14.3.1761. PMID: 23679270
Multidimensional independent predictors of cancer-related fatigue.
Hwang SS, Chang VT, Rue M, Kasimis B
J Pain Symptom Manage 2003 Jul;26(1):604-14. doi: 10.1016/s0885-3924(03)00218-5. PMID: 12850643

Diagnosis

Insulin resistance as a marker for the immune-metabolic subtype of depression.
Brouwer A, van Raalte DH, Lamers F, Rutters F, Elders PJM, Van Someren EJW, Snoek FJ, Beekman ATF, Bremmer MA
J Affect Disord 2021 Dec 1;295:1371-1376. Epub 2021 Sep 1 doi: 10.1016/j.jad.2021.08.151. PMID: 34565592
Irritability in Mood Disorders: Neurobiological Underpinnings and Implications for Pharmacological Intervention.
Bell E, Boyce P, Porter RJ, Bryant RA, Malhi GS
CNS Drugs 2021 Jun;35(6):619-641. Epub 2021 May 21 doi: 10.1007/s40263-021-00823-y. PMID: 34019255
Symptom burden in patients with chronic obstructive pulmonary disease.
Melhem O, Savage E, Lehane E
Appl Nurs Res 2021 Feb;57:151389. Epub 2020 Dec 1 doi: 10.1016/j.apnr.2020.151389. PMID: 33549292
Changes in the Network Structure of Post-traumatic Stress Disorder Symptoms Among Earthquake Exposed Adolescents in China: A 2-Year Longitudinal Study.
An Y, Hu CP, Zhao J, Chen Y, Wu X
Child Psychiatry Hum Dev 2021 Feb;52(1):104-113. doi: 10.1007/s10578-020-00995-6. PMID: 32342236
Irritability characteristics and parameters in an international sample.
Toohey MJ
J Affect Disord 2020 Feb 15;263:558-567. Epub 2019 Nov 9 doi: 10.1016/j.jad.2019.11.021. PMID: 31989992

Therapy

Exploring core symptoms and interrelationships among symptoms in children with acute leukemia during chemotherapy: A network analysis.
Fang J, Xu LL, Liu CQ, Zhu Z, Wang MX, Liu X, Liu Q, Huang HY, Lin Y
Support Care Cancer 2023 Sep 16;31(10):578. doi: 10.1007/s00520-023-08024-7. PMID: 37715817
Long-Term Favorable Effects of Physical Exercise on Burdensome Symptoms in the OptiTrain Breast Cancer Randomized Controlled Trial.
Wiggenraad F, Bolam KA, Mijwel S, van der Wall E, Wengström Y, Altena R
Integr Cancer Ther 2020 Jan-Dec;19:1534735420905003. doi: 10.1177/1534735420905003. PMID: 32090630Free PMC Article
Quality of life and chemotherapy-related symptoms of Turkish cancer children undergoing chemotherapy.
Arslan FT, Basbakkal Z, Kantar M
Asian Pac J Cancer Prev 2013;14(3):1761-8. doi: 10.7314/apjcp.2013.14.3.1761. PMID: 23679270
Safety practices, neurological symptoms, and pesticide poisoning.
Beseler C, Stallones L
J Occup Environ Med 2003 Oct;45(10):1079-86. doi: 10.1097/01.jom.0000085894.87332.36. PMID: 14534450
Multidimensional independent predictors of cancer-related fatigue.
Hwang SS, Chang VT, Rue M, Kasimis B
J Pain Symptom Manage 2003 Jul;26(1):604-14. doi: 10.1016/s0885-3924(03)00218-5. PMID: 12850643

Prognosis

Irritability in Mood Disorders: Neurobiological Underpinnings and Implications for Pharmacological Intervention.
Bell E, Boyce P, Porter RJ, Bryant RA, Malhi GS
CNS Drugs 2021 Jun;35(6):619-641. Epub 2021 May 21 doi: 10.1007/s40263-021-00823-y. PMID: 34019255
Identifying factors of psychological distress on the experience of pain and symptom management among cancer patients.
Baker TA, Krok-Schoen JL, McMillan SC
BMC Psychol 2016 Nov 2;4(1):52. doi: 10.1186/s40359-016-0160-1. PMID: 27806721Free PMC Article
Quality of life and chemotherapy-related symptoms of Turkish cancer children undergoing chemotherapy.
Arslan FT, Basbakkal Z, Kantar M
Asian Pac J Cancer Prev 2013;14(3):1761-8. doi: 10.7314/apjcp.2013.14.3.1761. PMID: 23679270
Relationship among subjective sleep complaints, headaches, and mood alterations following a mild traumatic brain injury.
Chaput G, Giguère JF, Chauny JM, Denis R, Lavigne G
Sleep Med 2009 Aug;10(7):713-6. Epub 2009 Jan 14 doi: 10.1016/j.sleep.2008.07.015. PMID: 19147402
Multidimensional independent predictors of cancer-related fatigue.
Hwang SS, Chang VT, Rue M, Kasimis B
J Pain Symptom Manage 2003 Jul;26(1):604-14. doi: 10.1016/s0885-3924(03)00218-5. PMID: 12850643

Clinical prediction guides

Prevalence of symptoms in children with acute lymphoblastic leukaemia: a systematic review and meta-analysis.
Lan X, Wu J, Liao Z, Wu Y, Hu R
BMC Cancer 2023 Nov 15;23(1):1113. doi: 10.1186/s12885-023-11581-z. PMID: 37968600Free PMC Article
Exploration of symptom clusters during hemodialysis and symptom network analysis of older maintenance hemodialysis patients: a cross-sectional study.
Zhou M, Gu X, Cheng K, Wang Y, Zhang N
BMC Nephrol 2023 Apr 27;24(1):115. doi: 10.1186/s12882-023-03176-4. PMID: 37106315Free PMC Article
Sex and Gender Impact Mental and Emotional Well-Being During COVID-19 Pandemic: A European Countries Experience.
Gisinger T, Dev R, Kautzky A, Harreiter J, Raparelli V, Kublickiene K, Trinidad Herrero M, Norris CM, Lavoie KL, Pilote L, Kautzky-Willer A
J Womens Health (Larchmt) 2022 Nov;31(11):1529-1539. doi: 10.1089/jwh.2022.0115. PMID: 36356181
Symptom prevalence, burden and correlates among people living with HIV in Vietnam: a two-centre self-report study.
Le Dai D, Pham TVA, Bui TTH, Than TNH, Pham VT, Luong NK, Harding R, Krakauer EL
AIDS Care 2022 Jul;34(7):887-893. Epub 2021 Jun 16 doi: 10.1080/09540121.2021.1922577. PMID: 34133248
Changes in the Network Structure of Post-traumatic Stress Disorder Symptoms Among Earthquake Exposed Adolescents in China: A 2-Year Longitudinal Study.
An Y, Hu CP, Zhao J, Chen Y, Wu X
Child Psychiatry Hum Dev 2021 Feb;52(1):104-113. doi: 10.1007/s10578-020-00995-6. PMID: 32342236

Recent systematic reviews

Prevalence of symptoms in children with acute lymphoblastic leukaemia: a systematic review and meta-analysis.
Lan X, Wu J, Liao Z, Wu Y, Hu R
BMC Cancer 2023 Nov 15;23(1):1113. doi: 10.1186/s12885-023-11581-z. PMID: 37968600Free PMC Article

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